Beilstein J. Org. Chem.2018,14, 1378–1388, doi:10.3762/bjoc.14.116
nuclei; cell-penetrating peptides; nucleoli; subcellulartargeting; Introduction
Various drugs act on targets that are located within the nucleus, the control center of the eukaryotic cell. A lipid bilayer membrane, which is perforated with nuclear pore complex structures through which the transfer of
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Graphical Abstract
Figure 1:
Circular dichroism spectra of the novel peptides solved in 10 mM phosphate buffer (pH 7) (A), or ph...